Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 2/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298239 | 1.00 | MAPT (0.38) | MAPTKDM4EADORA2AGLAALDH1A1 | |
| SCHEMBL28299546 | 1.00 | MAPT (0.38) | MAPTKDM4EADORA2AGLAALDH1A1 | |
| SCHEMBL27988321 | 0.82 | KDM4E (0.56) | MAPTKDM4EGLAALDH1A1HPGD | |
| SCHEMBL300896 | 0.82 | KDM4E (0.56) | MAPTKDM4EGLAALDH1A1HPGD | |
| SCHEMBL301230 | 0.82 | KDM4E (0.56) | MAPTKDM4EGLAALDH1A1HPGD | |
| SCHEMBL28299549 | 0.78 | ADORA2A (0.44) | KDM4EADORA2AHPGDADORA1SIGMAR1 | |
| SCHEMBL15205956 | 0.78 | ADORA2A (0.44) | KDM4EADORA2AHPGDADORA1SIGMAR1 | |
| SCHEMBL28298241 | 0.78 | ADORA2A (0.44) | KDM4EADORA2AHPGDADORA1SIGMAR1 | |
| SCHEMBL2322021 | 0.74 | ADORA2A (0.51) | KDM4EADORA2AHPGDADORA1 | |
| SCHEMBL29828788 | 0.74 | ADORA2A (0.51) | KDM4EADORA2AHPGDADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109846884-A | With TOR kinase inhibitor for treating cancer | 西格诺药品有限公司 | 2019-06-07 | — | — | CN | disclosed |