Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 16/20 | 0.66 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.66 |
| ▸ | PIK3CB | P42338 | 13/20 | 0.66 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.66 |
| ▸ | MTOR | P42345 | 2/20 | 0.43 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28873588 | 0.99 | PIK3CA (0.67) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL28299680 | 0.92 | PIK3CA (0.58) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL28298232 | 0.91 | PIK3CG (0.59) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL28029209 | 0.88 | PIK3CA (0.67) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL28028869 | 0.87 | PIK3CA (0.68) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL28298228 | 0.84 | PIK3CA (0.54) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL28298217 | 0.83 | PIK3CB (0.47) | PIK3CAPIK3CGPIK3CBPIK3CDADORA1 | |
| SCHEMBL28299566 | 0.82 | PIK3CB (0.47) | PIK3CAPIK3CGPIK3CBPIK3CDADORA1 | |
| SCHEMBL28785408 | 0.82 | PIK3CA (0.73) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL301238 | 0.81 | PIK3CB (0.98) | PIK3CAPIK3CGPIK3CBPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109846884-A | With TOR kinase inhibitor for treating cancer | 西格诺药品有限公司 | 2019-06-07 | — | — | CN | disclosed |