Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 14/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 14/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 12/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.58 |
| ▸ | MTOR | P42345 | 5/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.37 |
| ▸ | FGR | P09769 | 1/20 | 0.36 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.36 |
| ▸ | TXK | P42681 | 1/20 | 0.36 |
| ▸ | FRK | P42685 | 1/20 | 0.36 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28873588 | 0.93 | PIK3CA (0.67) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL28298250 | 0.92 | PIK3CA (0.66) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL28298232 | 0.90 | PIK3CG (0.59) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL28028885 | 0.88 | PIK3CA (0.58) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL301311 | 0.81 | PIK3CB (0.85) | PIK3CAPIK3CGPIK3CBPIK3CD | |
| SCHEMBL28028869 | 0.80 | PIK3CA (0.68) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL28029209 | 0.79 | PIK3CA (0.67) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL28298228 | 0.78 | PIK3CA (0.54) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL28029218 | 0.78 | PIK3CG (0.60) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR | |
| SCHEMBL28299587 | 0.78 | PIK3CD (0.47) | PIK3CAPIK3CGPIK3CBPIK3CDMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109846884-A | With TOR kinase inhibitor for treating cancer | 西格诺药品有限公司 | 2019-06-07 | — | — | CN | disclosed |