Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | APP | P05067 | 5/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831098 | 1.00 | PTPN1 (0.39) | PTPN1PPARAAPPPPARGMAOB | |
| SCHEMBL2830447 | 1.00 | PTPN1 (0.39) | PTPN1PPARAAPPPPARGMAOB | |
| SCHEMBL11301752 | 1.00 | PTPN1 (0.39) | PTPN1PPARAAPPPPARGMAOB | |
| SCHEMBL2831100 | 1.00 | PTPN1 (0.39) | PTPN1PPARAAPPPPARGMAOB | |
| SCHEMBL2835063 | 1.00 | PTPN1 (0.39) | PTPN1PPARAAPPPPARGMAOB | |
| SCHEMBL2829905 | 1.00 | PTPN1 (0.39) | PTPN1PPARAAPPPPARGMAOB | |
| SCHEMBL18621798 | 0.97 | PTPN1 (0.41) | PTPN1PPARAAPPPPARGMAOB | |
| SCHEMBL16274694 | 0.89 | APP (0.41) | APP | |
| SCHEMBL13360335 | 0.89 | APP (0.41) | APP | |
| SCHEMBL1036532 | 0.88 | PTPN1 (0.38) | PTPN1PPARAAPPPPARGMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213652-B1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | UNIV PENNSYLVANIA (US) | 2014-10-22 | — | — | EP | claimed |
| US-8465726-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-06-18 | — | — | US | claimed |
| US-20100266500-A1 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-10-21 | — | — | US | claimed |
| EP-2213652-B1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | UNIV PENNSYLVANIA (US) | 2014-10-22 | — | — | EP | disclosed |
| US-8465726-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-06-18 | — | — | US | disclosed |
| US-7858072-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-12-28 | — | — | US | disclosed |
| US-20100266500-A1 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-10-21 | — | — | US | disclosed |
| US-7807135-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-10-05 | — | — | US | disclosed |
| EP-2213652-A1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | The Trustees of The University of Pennsylvania (US) | 2010-08-04 | — | — | EP | disclosed |
| EP-1841465-A4 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | UNIV PENNSYLVANIA (US) | 2009-04-01 | — | — | EP | disclosed |
| EP-1838298-A4 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | UNIV PENNSYLVANIA (US) | 2009-03-04 | — | — | EP | disclosed |
| EP-1841465-A2 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | The Trustees of The University of Pennsylvania (US) | 2007-10-10 | — | — | EP | disclosed |
| EP-1838298-A2 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | The Trustees of The University of Pennsylvania (US) | 2007-10-03 | — | — | EP | disclosed |
| US-20060269474-A1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-11-30 | — | — | US | disclosed |
| US-20060269473-A1 | Stilbene derivatives and their use for binding and imaging amyoid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-11-30 | — | — | US | disclosed |
| WO-2006078384-A2 | STILBENE DERIVATIVES AND THEIR USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-07-27 | — | — | WO | disclosed |
| WO-2006066104-A2 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060269473-A1 | Stilbene derivatives and their use for binding and imaging amyoid plaques | IAPP, APP, APBA1 | PTPN1 4502/4885PPARA 1597/4885APP 2/4885 |
| US-20100266500-A1 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | APP, APBA1, PSEN1 | PTPN1 4661/4885PPARA 2095/4885APP 1/4885 |
| US-20060269474-A1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | APP, APBA1, PSEN1 | PTPN1 4661/4885PPARA 2095/4885APP 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.