SCHEMBL11301752

SCHEMBL11301752

CN(C(=O)OC(C)(C)C)c1ccc(/C=C/c2ccc(OCCOCCOCCOS(C)(=O)=O)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.39
PPARA Q07869 6/20 0.38
APP P05067 5/20 0.37
PPARG P37231 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2831098 1.00 PTPN1 (0.39) PTPN1PPARAAPPPPARGMAOB
SCHEMBL2830447 1.00 PTPN1 (0.39) PTPN1PPARAAPPPPARGMAOB
SCHEMBL2831100 1.00 PTPN1 (0.39) PTPN1PPARAAPPPPARGMAOB
SCHEMBL2829909 1.00 PTPN1 (0.39) PTPN1PPARAAPPPPARGMAOB
SCHEMBL2835063 1.00 PTPN1 (0.39) PTPN1PPARAAPPPPARGMAOB
SCHEMBL2829905 1.00 PTPN1 (0.39) PTPN1PPARAAPPPPARGMAOB
SCHEMBL18621798 0.97 PTPN1 (0.41) PTPN1PPARAAPPPPARGMAOB
SCHEMBL16274694 0.89 APP (0.41) APP
SCHEMBL13360335 0.89 APP (0.41) APP
SCHEMBL1036532 0.88 PTPN1 (0.38) PTPN1PPARAAPPPPARGMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10392344-B2 Method for preparing fluorine-18 eluent with adjusted PH, and method for labelling fluorine-18 using same THE ASAN FOUNDATION (KR) 2019-08-27 US claimed
EP-2575898-B1 METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGAND LIFE MOLECULAR IMAGING SA (CH) 2020-09-30 EP disclosed
EP-2575898-B1 METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGAND LIFE MOLECULAR IMAGING SA (CH) 2020-09-30 EP disclosed
US-10392344-B2 Method for preparing fluorine-18 eluent with adjusted PH, and method for labelling fluorine-18 using same THE ASAN FOUNDATION (KR) 2019-08-27 US disclosed
EP-2579902-B2 METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS PIRAMAL IMAGING SA (CH) 2019-08-14 EP disclosed
EP-2590683-B1 METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS PIRAMAL IMAGING SA (CH) 2017-10-18 EP disclosed
EP-2590683-B1 METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS PIRAMAL IMAGING SA (CH) 2017-10-18 EP disclosed
EP-2579902-B1 METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS PIRAMAL IMAGING SA (CH) 2017-07-12 EP disclosed
EP-2579902-B1 METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS PIRAMAL IMAGING SA (CH) 2017-07-12 EP disclosed
US-9592308-B2 Method for production of F-18 labeled amyloid beta ligands PIRAMAL IMAGING SA (CH) 2017-03-14 US disclosed
US-20120184749-A1 Usage of low to medium-pressure liquid chromatography for the purification of radiotracers BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-07-19 US disclosed
WO-2011151283-A1 METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2011-12-08 WO disclosed
WO-2011151281-A1 METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2011-12-08 WO disclosed
WO-2011151282-A1 METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGAND BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2011-12-08 WO disclosed
WO-2011151282-A1 METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGAND BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2011-12-08 WO disclosed
WO-2011151273-A1 METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2011-12-08 WO disclosed
WO-2011151283-A1 METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2011-12-08 WO disclosed
WO-2011003591-A1 USAGE OF LOW TO MEDIUM-PRESSURE LIQUID CHROMATOGRAPHY FOR THE PURIFICATION OF RADIOTRACERS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-01-13 WO disclosed
US-20100113763-A1 METHOD FOR PREPARATION OF ORGANOFLUORO COMPOUNDS IN ALCOHOL SOLVENTS FUTURECHEM CO., LTD. (KR) 2010-05-06 US disclosed
US-20100113763-A1 METHOD FOR PREPARATION OF ORGANOFLUORO COMPOUNDS IN ALCOHOL SOLVENTS FUTURECHEM CO., LTD. (KR) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120184749-A1 Usage of low to medium-pressure liquid chromatography for the purification of radiotracers TMEM14C, SLC5A7, SLC43A1 PTPN1 1316/4885PPARA 3419/4885APP 1292/4885
US-10392344-B2 Method for preparing fluorine-18 eluent with adjusted PH, and method for labelling fluorine-18 using same PHF8, AFF1, F8 PTPN1 1435/4885PPARA 3006/4885APP 3973/4885
US-20100113763-A1 METHOD FOR PREPARATION OF ORGANOFLUORO COMPOUNDS IN ALCOHOL SOLVENTS AFF1, AFF4, PFAS PTPN1 2916/4885PPARA 2270/4885APP 2771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.