SCHEMBL28299170

SCHEMBL28299170

FC(F)(F)c1ccc(-c2cc3cccc4c5cccc6cccc(c(c2-c2ccc(C(F)(F)F)cc2)c34)c65)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 4/20 0.38
MAPT P10636 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
KIF11 P52732 1/20 0.36
CYP1A2 P05177 3/20 0.36
ERBB2 P04626 1/20 0.36
FYN P06241 1/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36
AHR P35869 1/20 0.36
TOP1 P11387 3/20 0.35
MAOB P27338 1/20 0.34
THRB P10828 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PARP1 P09874 1/20 0.34
TNKS O95271 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14241182 0.82 CYP1A2 (0.43) ENPP1MAPTALDH1A1MEN1GAA
SCHEMBL2852878 0.82 CYP1A2 (0.46) ENPP1MAPTALDH1A1MEN1KMT2A
SCHEMBL18088225 0.79 ENPP1 (0.43) ENPP1MAPTALDH1A1MEN1GAA
SCHEMBL13408701 0.78 KIF11 (0.50) ENPP1ALDH1A1KIF11CYP1A2TOP1
SCHEMBL22911474 0.76 CYP1A2 (0.53) ENPP1MAPTALDH1A1MEN1GAA
SCHEMBL4886590 0.76 MEN1 (0.45) ENPP1MAPTALDH1A1MEN1KMT2A
SCHEMBL24604987 0.75 ESR1 (0.44) MAPTALDH1A1MEN1GAAKMT2A
SCHEMBL985118 0.75 CYP1A2 (0.46) ALDH1A1MEN1KMT2ACYP1A2ERBB2
SCHEMBL12402901 0.74 KIF11 (0.58) ALDH1A1KIF11CYP1A2TNKSCYP1A1
SCHEMBL24605138 0.73 CYP1A2 (0.41) ENPP1MAPTALDH1A1KIF11CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104024891-B For correcting the optical element of colour blindness 日东电工株式会社 2019-06-28 CN disclosed