SCHEMBL28299176

SCHEMBL28299176

O=CC1CCCCCCCNCCCC1

nearest known ligand 0.70

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
EPHX1 P07099 1/20 0.34
ADH1A P07327 3/20 0.32
ADH1C P00326 2/20 0.32
ADH1B P00325 1/20 0.32
ADH4 P08319 1/20 0.32
CXCR4 P61073 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26870681 1.00 ALDH1A1 (0.45) ALDH1A1EPHX1ADH1AADH1CADH1B
SCHEMBL28317190 1.00 ALDH1A1 (0.45) ALDH1A1EPHX1ADH1AADH1CADH1B
Piperidine SCHEMBL971397 1.00 ALDH1A1 (0.45) ALDH1A1EPHX1ADH1AADH1CADH1B
SCHEMBL28318269 0.98 ALDH1A1 (0.43) ALDH1A1EPHX1ADH1AADH1CADH1B
SCHEMBL28317188 0.95 ALDH1A1 (0.41) ALDH1A1EPHX1ADH1AADH1CADH1B
SCHEMBL519071 0.93 ALDH1A1 (0.36) ALDH1A1EPHX1CXCR4SMN1; SMN2
SCHEMBL28318201 0.90 SMN1; SMN2 (0.35) ALDH1A1CXCR4SMN1; SMN2
SCHEMBL518657 0.86 ALDH1A1 (0.35) ALDH1A1ADH1AADH1CADH1BADH4
SCHEMBL28317187 0.86 ALDH1A1 (0.35) ALDH1A1ADH1AADH1CADH1BADH4
SCHEMBL28317192 0.86 ALDH1A1 (0.35) ALDH1A1ADH1AADH1CADH1BADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109748942-A A kind of macrolides compound 普莱柯生物工程股份有限公司 2019-05-14 CN claimed
CN-110099869-A Thermally responsive solution and method of use thereof 阿克福特斯技术有限公司 2019-08-06 CN disclosed
CN-109748942-A A kind of macrolides compound 普莱柯生物工程股份有限公司 2019-05-14 CN disclosed