Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 12/20 | 0.67 |
| ▸ | THRA | P10827 | 6/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11706311 | 1.00 | THRB (0.67) | THRBTHRATP53TSHRPTPN11 | |
| SCHEMBL27389920 | 0.98 | THRB (0.64) | THRBTHRATP53TSHRPTPN11 | |
| SCHEMBL8876412 | 0.95 | THRB (0.60) | THRBTHRAPTPN11 | |
| SCHEMBL11062461 | 0.88 | THRB (0.67) | THRBTHRATP53TSHRPTPN11 | |
| SCHEMBL20556237 | 0.88 | THRB (0.67) | THRBTHRATP53TSHRPTPN11 | |
| SCHEMBL9626788 | 0.88 | THRB (0.67) | THRBTHRATP53TSHRPTPN11 | |
| SCHEMBL9628337 | 0.88 | THRB (0.67) | THRBTHRATP53TSHRPTPN11 | |
| SCHEMBL20556403 | 0.88 | THRB (0.67) | THRBTHRATP53TSHRPTPN11 | |
| SCHEMBL9627118 | 0.88 | THRB (0.67) | THRBTHRATP53TSHRPTPN11 | |
| SCHEMBL13617723 | 0.87 | THRB (0.65) | THRBTHRATP53TSHRPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715202-A | Compounds, compositions and methods for treating diseases | 斯必乐维生物科学公司 | 2019-05-03 | — | — | CN | disclosed |