Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 14/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 14/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 14/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821909 | 0.87 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CAMTOR | |
| SCHEMBL28298290 | 0.84 | PIK3CG (0.43) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL28299780 | 0.82 | PIK3CD (0.45) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL28298209 | 0.81 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL1750367 | 0.80 | PIK3CD (0.58) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL28298218 | 0.80 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL28299576 | 0.80 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CAMTOR | |
| SCHEMBL28299571 | 0.80 | PIK3CD (0.53) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL28299551 | 0.80 | PIK3CD (0.47) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL28873588 | 0.79 | PIK3CA (0.67) | PIK3CDPIK3CBPIK3CGPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109846884-A | With TOR kinase inhibitor for treating cancer | 西格诺药品有限公司 | 2019-06-07 | — | — | CN | disclosed |