SCHEMBL28299607

SCHEMBL28299607

NS(=O)(=O)c1cc(S(=O)(=O)CO)cs1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CA2 P00918 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28047295 0.80 CA2 (0.59) CA2
SCHEMBL28047293 0.79 CA2 (0.59) CA2
SCHEMBL15881245 0.75 CA2 (0.54) CA2
SCHEMBL15880654 0.74 CA2 (0.54) CA2
SCHEMBL7145362 0.73 CA2 (0.50) CA2
SCHEMBL28047292 0.71 CA2 (0.50) CA2
SCHEMBL6927505 0.69 CA2 (0.71) CA2
SCHEMBL24670388 0.68 CA2 (0.50) CA2
SCHEMBL20651640 0.68 CA2 (0.47) CA2
SCHEMBL5149907 0.67 CA2 (0.52) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110179777-A Medical composition comprising nitroxyl donors 卡尔迪奥克斯尔制药公司 2019-08-30 CN disclosed
CN-105142627-B Pharmaceutical compositions comprising nitroxyl donors 卡尔迪奥克斯尔制药公司 2019-06-21 CN disclosed