Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28299623

C1CCOC1.CCCCCCCCCCCCCCCOP(=O)(O)O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 14/20 0.75
LPAR2 Q9HBW0 11/20 0.75
LPAR1 Q92633 8/20 0.75
CDC25A P30304 1/20 0.49
LPAR5 Q9H1C0 2/20 0.49
ENPP2 Q13822 2/20 0.45
LPAR6 P43657 1/20 0.45
LPAR4 Q99677 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL27900225 1.00 LPAR3 (0.75) LPAR3LPAR2LPAR1CDC25ALPAR5
Tetrahydrofuran SCHEMBL28178307 0.98 LPAR3 (0.71) LPAR3LPAR2LPAR1CDC25ALPAR5
Oxirane SCHEMBL7164231 0.93 LPAR3 (0.81) LPAR3LPAR2LPAR1CDC25ALPAR5
Phosphoric Acid Monododecyl Ester SCHEMBL2049086 0.93 LPAR3 (0.81) LPAR3LPAR2LPAR1CDC25ALPAR5
SCHEMBL7557287 0.93 LPAR3 (0.74) LPAR3LPAR2LPAR1CDC25ALPAR5
Hexadecyl Dihydrogen Phosphate SCHEMBL10533860 0.89 LPAR3 (0.88) LPAR3LPAR2LPAR1LPAR5
Phosphoric Acid Monododecyl Ester SCHEMBL27793114 0.89 LPAR3 (0.95) LPAR3LPAR2LPAR1LPAR5
Fluoride SCHEMBL28218528 0.89 LPAR3 (0.95) LPAR3LPAR2LPAR1LPAR5
Phosphoric Acid Monodecyl Ester SCHEMBL27465279 0.89 LPAR3 (0.95) LPAR3LPAR2LPAR1LPAR5
SCHEMBL2788530 0.87 LPAR3 (0.77) LPAR3LPAR2LPAR1CDC25ALPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107641091-B A kind of preparation method of β-apo- -12 '-carrot aldehyde 肇庆巨元生化有限公司 2019-05-17 CN disclosed