SCHEMBL28299711

SCHEMBL28299711

O=C(c1ccc(Cl)cc1)N(O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.62
HPGD P15428 1/20 0.62
CES2 O00748 2/20 0.53
CES1 P23141 2/20 0.53
ALOX15 P16050 2/20 0.53
MAPT P10636 2/20 0.53
ALDH1A1 P00352 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
HSD17B10 Q99714 1/20 0.53
TSHR P16473 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.46
NR4A1 P22736 1/20 0.46
CHRM2 P08172 1/20 0.46
CHRM3 P20309 1/20 0.46
LMNA P02545 1/20 0.45
SRD5A2 P31213 1/20 0.44
BACE1 P56817 1/20 0.44
CYP1B1 Q16678 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28930325 0.92 ALOX15 (0.57) KDM4EHPGDCES2CES1ALOX15
SCHEMBL873994 0.90 HPGD (0.72) KDM4EHPGDCES2CES1MAPT
SCHEMBL133668 0.86 KDM4E (0.67) KDM4EHPGDCES2CES1MAPT
SCHEMBL23511690 0.84 HPGD (0.66) KDM4EHPGDMAPTALDH1A1SMN1; SMN2
SCHEMBL28828108 0.84 KDM4E (0.65) KDM4EHPGDCES2CES1MAPT
SCHEMBL11682285 0.84 KDM4E (0.65) KDM4EHPGDCES2CES1MAPT
SCHEMBL11270838 0.84 KDM4E (0.65) KDM4EHPGDCES2CES1MAPT
Ammonia Solution, Strong SCHEMBL11681866 0.84 KDM4E (0.65) KDM4EHPGDCES2CES1MAPT
SCHEMBL11256252 0.84 KDM4E (0.65) KDM4EHPGDCES2CES1MAPT
SCHEMBL27464950 0.84 KDM4E (0.65) KDM4EHPGDCES2CES1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109772245-A Nanometer organic complex function microreactor construct and sulfuric acid molten aluminum in iron separation method 山西大学 2019-05-21 CN claimed
CN-109772245-A Nanometer organic complex function microreactor construct and sulfuric acid molten aluminum in iron separation method 山西大学 2019-05-21 CN disclosed