Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31500051 | 0.87 | NPC1 (0.71) | RAB9ASMN1; SMN2NPC1POLBHPGD | |
| SCHEMBL8765128 | 0.83 | SMN1; SMN2 (0.67) | RAB9ASMN1; SMN2NPC1POLBHPGD | |
| SCHEMBL28299664 | 0.82 | CYP1A2 (0.54) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL28301087 | 0.81 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2NPC1POLBHPGD | |
| SCHEMBL21208579 | 0.80 | SMN1; SMN2 (0.57) | RAB9ASMN1; SMN2NPC1POLBHPGD | |
| SCHEMBL30000594 | 0.79 | LMNA (0.57) | RAB9ASMN1; SMN2NPC1POLBHPGD | |
| SCHEMBL31500066 | 0.78 | SMN1; SMN2 (0.59) | RAB9ASMN1; SMN2NPC1POLBHPGD | |
| SCHEMBL28847573 | 0.78 | SMN1; SMN2 (0.54) | RAB9ASMN1; SMN2NPC1POLBHPGD | |
| SCHEMBL16872802 | 0.78 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2NPC1POLBHPGD | |
| SCHEMBL28299531 | 0.78 | CYP1A2 (0.52) | RAB9ASMN1; SMN2NPC1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890822-A | INHIBITORS OF CELLULAR METABOLIC PROCESSES | 安吉奥斯医药品有限公司 | 2019-06-14 | — | — | CN | disclosed |