Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301157 | 0.83 | KDM4E (0.70) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL15205743 | 0.79 | USP1 (0.47) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL28298231 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL28299583 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL28299567 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL28298233 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL28298230 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL28298224 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL28298221 | 0.72 | KDM4E (0.44) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL28299693 | 0.71 | KDM4E (0.46) | KDM4EALDH1A1HPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109846884-A | With TOR kinase inhibitor for treating cancer | 西格诺药品有限公司 | 2019-06-07 | — | — | CN | disclosed |