SCHEMBL28299778

SCHEMBL28299778

CC(C)(C)c1ccc(CCC(=O)OP(O)O)c(C(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 5/20 0.36
ADAM17 P78536 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
HSP90AA1 P07900 1/20 0.35
HSP90AB1 P08238 1/20 0.35
CYP2C19 P33261 2/20 0.34
CYP1A2 P05177 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28242806 0.82 APEX1 (0.43) NR1H4ADAM17NPSR1HSP90AA1HSP90AB1
SCHEMBL29040644 0.80 NR1H4 (0.52) NR1H4ADAM17NPSR1CYP2C19SMN1; SMN2
SCHEMBL31222192 0.77 CYP1A2 (0.40) NR1H4CYP2C19CYP1A2GAALMNA
SCHEMBL10442609 0.76 CYP1A2 (0.47) CYP2C19CYP1A2GAALMNAMAPT
SCHEMBL27862063 0.74 CYP2C19 (0.38) NR1H4CYP2C19CYP1A2GAALMNA
SCHEMBL9259675 0.73 CYP2C19 (0.43) NR1H4HSP90AA1HSP90AB1CYP2C19CYP1A2
SCHEMBL7950344 0.73 CYP1A2 (0.33) CYP2C19CYP1A2SMN1; SMN2GAACYP2D6
SCHEMBL7157824 0.73 CYP1A2 (0.33) CYP2C19CYP1A2SMN1; SMN2GAACYP2D6
SCHEMBL17266677 0.73 ALOX5 (0.50) GAALMNA
SCHEMBL2895917 0.73 CYP1A2 (0.33) CYP2C19CYP1A2SMN1; SMN2GAACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109777089-A A kind of nylon material and preparation method thereof 江苏博云塑业股份有限公司 2019-05-21 CN disclosed