Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DUT | P33316 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2719765 | 0.83 | CRBN (0.54) | CRBNDDB1PKMPOLBHSD17B10 | |
| SCHEMBL3235862 | 0.80 | CRBN (0.50) | CRBNDDB1PKMPOLBHSD17B10 | |
| SCHEMBL1344880 | 0.80 | CRBN (0.50) | CRBNDDB1PKMPOLBHSD17B10 | |
| SCHEMBL27411171 | 0.80 | CRBN (0.50) | CRBNDDB1PKMPOLBHSD17B10 | |
| SCHEMBL24211424 | 0.80 | CRBN (0.50) | CRBNDDB1PKMPOLBHSD17B10 | |
| SCHEMBL24923587 | 0.80 | CRBN (0.50) | CRBNDDB1PKMPOLBHSD17B10 | |
| SCHEMBL2990979 | 0.80 | CRBN (0.50) | CRBNDDB1PKMPOLBHSD17B10 | |
| SCHEMBL20850213 | 0.77 | CRBN (0.47) | CRBNDDB1PKMPOLBHSD17B10 | |
| SCHEMBL22666465 | 0.77 | CRBN (0.47) | CRBNDDB1PKMPOLBHSD17B10 | |
| SCHEMBL9065010 | 0.77 | CRBN (0.47) | CRBNDDB1PKMPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101253199-B | Agonists, antagonists and immunotoxins for immunomodulating tumor necrosis factor receptor 25(TNFR25) | 迈阿密大学 | 2019-06-14 | — | — | CN | disclosed |