SCHEMBL2990979

SCHEMBL2990979

CC(N)n1ccc(=O)[nH]c1=O

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.50
DDB1 Q16531 1/20 0.41
PKM P14618 1/20 0.41
POLB P06746 1/20 0.35
HSD17B10 Q99714 1/20 0.35
DUT P33316 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1344880 1.00 CRBN (0.50) CRBNDDB1PKMPOLBHSD17B10
SCHEMBL2719765 0.83 CRBN (0.54) CRBNDDB1PKMPOLBHSD17B10
SCHEMBL24211424 0.80 CRBN (0.50) CRBNDDB1PKMPOLBHSD17B10
SCHEMBL3235862 0.80 CRBN (0.50) CRBNDDB1PKMPOLBHSD17B10
SCHEMBL24923587 0.80 CRBN (0.50) CRBNDDB1PKMPOLBHSD17B10
SCHEMBL2983403 0.80 CRBN (0.50) CRBNDDB1PKMPOLBHSD17B10
SCHEMBL20850213 0.77 CRBN (0.47) CRBNDDB1PKMPOLBHSD17B10
SCHEMBL22666465 0.77 CRBN (0.47) CRBNDDB1PKMPOLBHSD17B10
SCHEMBL9065010 0.77 CRBN (0.47) CRBNDDB1PKMPOLBHSD17B10
SCHEMBL21919776 0.76 CRBN (0.46) CRBNDDB1PKMPOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023212369-A1 NUCLEOTIDE CYCLIC CLEAVABLE MOIETIES AND USES THEREOF Singular Genomics Systems, Inc. (US) 2023-11-02 WO disclosed
EP-4115908-A1 EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY Sarepta Therapeutics, Inc. (US) 2023-01-11 EP disclosed
WO-2020214763-A1 COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY SAREPTA THERAPEUTICS, INC. (US) 2020-10-22 WO disclosed
US-7777024-B2 Process for preparing a pentopyranosyl nucleic acid conjugate AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. (DE) 2010-08-17 US disclosed
US-20090221793-A1 PROCESS FOR PREPARING A PENTOPYRANOSYL NUCLEIC ACID CONJUGATE SANOFI-AVENTIS S.A. (FR) 2009-09-03 US disclosed
US-7501506-B2 Pentopyranosyl nucleic acid conjugates NANOGEN RECOGNOMICS GMBH (DE) 2009-03-10 US disclosed
US-7153955-B2 Pentopyranosyl nucleic acid arrays, and uses thereof NANOGEN RECOGNOMICS GMBH (DE) 2006-12-26 US disclosed
US-20060270840-A1 Pentopyranosyl nucleic acid conjugates SANOFI-AVENTIS S.A. (FR) 2006-11-30 US disclosed
EP-1034180-B1 LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME NANOGEN RECOGNOMICS GMBH (DE) 2006-03-29 EP disclosed
US-20050053945-A1 Process for the preparation of a pentopyranosyl conjugate NANOGEN RECOGNOMICS GMBH 2005-03-10 US disclosed
EP-1070079-A2 METHOD FOR THE PRODUCTION OF PENTOPYRANOSYL NUCLEOSIDES Nanogen Recognomics GmbH (DE) 2001-01-24 EP disclosed
EP-1034180-A2 LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME Nanogen Recognomics GmbH (DE) 2000-09-13 EP disclosed
EP-1019423-A2 METHOD FOR PRODUCING A PENTOPYRANOSYL NUCLEOSIDE Nanogen Recognomics GmbH (DE) 2000-07-19 EP disclosed
EP-1017704-A2 USE OF A PENTOPYRANOSYL NUCLEOSIDE CONTAINING CONJUGATE FOR PRODUCING AN ARRAY Nanogen Recognomics GmbH (DE) 2000-07-12 EP disclosed
EP-1017703-A2 PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME Nanogen Recognomics GmbH (DE) 2000-07-12 EP disclosed
WO-1999052923-A2 METHOD FOR THE PRODUCTION OF PENTOPYRANOSYL NUCLEOSIDES AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-10-21 WO disclosed
WO-1999015540-A2 METHOD FOR PRODUCING A PENTOPYRANOSYL NUCLEOSIDE AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 1999-04-01 WO disclosed
WO-1999015542-A2 LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-04-01 WO disclosed
WO-1999015541-A2 USE OF A PENTOPYRANOSYL NUCLEOSIDE FOR PRODUCING AN ELECTRONIC COMPONENT, AND CONJUGATES OF SAID PENTOPYRANOSYL NUCLEOSIDE AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-04-01 WO disclosed
WO-1999015539-A2 PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221793-A1 PROCESS FOR PREPARING A PENTOPYRANOSYL NUCLEIC ACID CONJUGATE RNGTT, NT5C3B, FUT6 CRBN 1660/4885DDB1 350/4885PKM 2021/4885
US-20050053945-A1 Process for the preparation of a pentopyranosyl conjugate FUT6, FUT5, FUCA2 CRBN 3383/4885DDB1 3687/4885PKM 1264/4885
US-20060270840-A1 Pentopyranosyl nucleic acid conjugates FUT6, RNGTT, B3GAT3 CRBN 2361/4885DDB1 323/4885PKM 2810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.