Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.34 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| [1,4']Bipiperidinyl SCHEMBL352141 | 0.97 | HTR6 (0.52) | HTR6L3MBTL3L3MBTL1MBTD1CYP2D6 | |
| SCHEMBL3159634 | 0.97 | HTR6 (0.52) | HTR6L3MBTL3L3MBTL1MBTD1CYP2D6 | |
| [1,4']Bipiperidinyl SCHEMBL42685 | 0.97 | HTR6 (0.52) | HTR6L3MBTL3L3MBTL1MBTD1CYP2D6 | |
| [1,4']Bipiperidinyl SCHEMBL2250608 | 0.95 | HTR6 (0.50) | HTR6L3MBTL3L3MBTL1MBTD1CYP2D6 | |
| Hydrochloric Acid SCHEMBL5235217 | 0.95 | HTR6 (0.50) | HTR6L3MBTL3L3MBTL1MBTD1CYP2D6 | |
| [1,4']Bipiperidinyl SCHEMBL19410113 | 0.95 | HTR6 (0.50) | HTR6L3MBTL3L3MBTL1MBTD1CYP2D6 | |
| Hydrochloric Acid SCHEMBL5322658 | 0.95 | HTR6 (0.50) | HTR6L3MBTL3L3MBTL1MBTD1CYP2D6 | |
| Hydrochloric Acid SCHEMBL3571227 | 0.95 | HTR6 (0.50) | HTR6L3MBTL3L3MBTL1MBTD1CYP2D6 | |
| [1,4']Bipiperidinyl SCHEMBL7031476 | 0.95 | HTR6 (0.50) | HTR6L3MBTL3L3MBTL1MBTD1CYP2D6 | |
| [1,4']Bipiperidinyl SCHEMBL27748186 | 0.95 | HTR6 (0.50) | HTR6L3MBTL3L3MBTL1MBTD1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796462-A | A kind of preparation method of irinotecan hydrochloride | 辰欣药业股份有限公司 | 2019-05-24 | — | — | CN | disclosed |