Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28300077

N.O=S(=O)=NCCc1cnon1

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28218983 0.63
SCHEMBL27557509 0.62
SCHEMBL28300076 0.61 CA2 (0.42)
SCHEMBL3751577 0.61
SCHEMBL12641989 0.61
SCHEMBL30499009 0.59
SCHEMBL13183720 0.57 NPC1 (0.31)
SCHEMBL27841484 0.54 GFER (0.52)
SCHEMBL277059 0.52
SCHEMBL13752371 0.51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109897011-A A kind of IDO inhibitor and its application 上海华汇拓医药科技有限公司 2019-06-18 CN disclosed