Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 12/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128907 | 0.85 | APP (0.46) | APPLMNASLC6A6CYP2C19BLM | |
| Hydrochloric Acid SCHEMBL3148714 | 0.83 | APP (0.44) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL5017073 | 0.83 | APP (0.44) | APPLMNASLC6A6CYP2C19BLM | |
| Water SCHEMBL21226523 | 0.83 | APP (0.44) | APPLMNASLC6A6CYP2C19BLM | |
| Water SCHEMBL30397698 | 0.81 | APP (0.42) | APPLMNASLC6A6CYP2C19BLM | |
| Dimethylamine SCHEMBL918206 | 0.79 | APP (0.41) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL353885 | 0.79 | ALDH1A1 (0.48) | APPLMNASLC6A6CYP2C19BLM | |
| Acrylamide SCHEMBL29113250 | 0.78 | ALDH1A1 (0.39) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL28560997 | 0.78 | APP (0.39) | APPLMNASLC6A6CYP2C19BLM | |
| Glycine SCHEMBL14742258 | 0.77 | GLRA1 (0.48) | GLRA1SLC6A9OR51E2KDM4AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109789065-A | Cosmetic composition for combating the loss of colour of dyed material | 因诺斯佩克有限公司 | 2019-05-21 | — | — | CN | disclosed |