SCHEMBL28300643

SCHEMBL28300643

CC(=COC(C)O)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.35
TP53 P04637 1/20 0.33
AKR1C3 P42330 1/20 0.31
APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27629560 0.83 TSHR (0.36) PTGS1AKR1C3APEX1
SCHEMBL28361257 0.79 PTGS1 (0.30) PTGS1AKR1C3
SCHEMBL27981041 0.79 TP53 (0.32) PTGS1TP53AKR1C3
SCHEMBL19439502 0.79 PTGS1 (0.30) PTGS1AKR1C3
SCHEMBL19439501 0.77
SCHEMBL4110882 0.73 MEN1 (0.31)
SCHEMBL8503687 0.73 LMNA (0.41)
SCHEMBL1865884 0.71 PTGS1 (0.37) PTGS1AKR1C3APEX1
SCHEMBL1865885 0.71 PTGS1 (0.37) PTGS1AKR1C3APEX1
SCHEMBL22042686 0.69 TDP1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110054715-A The manufacturing method of polyethylene polymer and polymer composition containing polar comonomers 埃克森美孚化学专利公司 2019-07-26 CN disclosed
CN-104203394-B Polyethylene polymers containing polar comonomers and process for making polymer compositions 埃克森美孚化学专利公司 2019-06-07 CN disclosed