Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11597360 | 0.90 | PRMT1 (0.55) | PRMT1RAB9AKDM4EALDH1A1HTR2A | |
| SCHEMBL11597357 | 0.90 | PRMT1 (0.55) | PRMT1RAB9AKDM4EALDH1A1HTR2A | |
| SCHEMBL25597192 | 0.84 | FLT3 (0.39) | PRMT1RAB9AALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL3299029 | 0.83 | RAB9A (0.50) | PRMT1RAB9AKDM4EALDH1A1HTR2A | |
| SCHEMBL3299030 | 0.83 | RAB9A (0.50) | PRMT1RAB9AKDM4EALDH1A1HTR2A | |
| SCHEMBL2189821 | 0.82 | KDM4E (0.52) | RAB9AKDM4EMEN1KMT2AHTR2A | |
| SCHEMBL17066108 | 0.82 | KDM4E (0.52) | RAB9AKDM4EMEN1KMT2AHTR2A | |
| SCHEMBL1930698 | 0.82 | KDM4E (0.52) | RAB9AKDM4EMEN1KMT2AHTR2A | |
| SCHEMBL14275030 | 0.82 | KDM4E (0.52) | PRMT1RAB9AKDM4EALDH1A1HTR2A | |
| SCHEMBL2770961 | 0.82 | KDM4E (0.55) | PRMT1RAB9AKDM4EALDH1A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110945076-B | Transmembrane pH-gradient polymer vesicles for quantification of ammonia in body fluids | 苏黎士联邦理工大学 | 2023-10-17 | — | — | CN | disclosed |
| CN-109803685-A | Transmembrane pH-gradient polymersome and use thereof for scavenging ammonia and methylated analogs of ammonia | 瑞士苏黎世联邦理工学院 | 2019-05-24 | — | — | CN | disclosed |