Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 11/20 | 0.49 |
| ▸ | CA2 | P00918 | 11/20 | 0.49 |
| ▸ | CA12 | O43570 | 7/20 | 0.49 |
| ▸ | CA9 | Q16790 | 7/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5213233 | 0.89 | TDP1 (0.53) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL28210550 | 0.87 | TDP1 (0.70) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL917886 | 0.86 | TDP1 (0.64) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL5908856 | 0.84 | TDP1 (0.57) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL22829019 | 0.84 | TDP1 (0.57) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL12282152 | 0.83 | TDP1 (0.56) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL12972387 | 0.83 | TDP1 (0.47) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL569251 | 0.82 | TDP1 (0.74) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL3020258 | 0.82 | TDP1 (0.81) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL21494308 | 0.82 | TDP1 (0.64) | TDP1MEN1GAAKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897011-B | IDO inhibitor and application thereof | 上海华汇拓医药科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-109897011-A | A kind of IDO inhibitor and its application | 上海华汇拓医药科技有限公司 | 2019-06-18 | — | — | CN | disclosed |