Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27627070 | 0.84 | HCAR2 (0.52) | MEN1KMT2AMMP1MMP2MMP9 | |
| SCHEMBL27698218 | 0.83 | KMT2A (0.61) | MEN1KMT2ASMN1; SMN2L3MBTL1MMP1 | |
| Hydrochloric Acid SCHEMBL27698236 | 0.82 | KMT2A (0.59) | MEN1KMT2ASMN1; SMN2L3MBTL1MMP1 | |
| SCHEMBL19949252 | 0.81 | MMP1 (0.48) | MEN1KMT2ASMN1; SMN2L3MBTL1MMP1 | |
| SCHEMBL1334643 | 0.79 | KDM4E (0.40) | MEN1KMT2ASMN1; SMN2L3MBTL1RAB9A | |
| Hydrochloric Acid SCHEMBL1336116 | 0.78 | KDM4E (0.40) | MEN1KMT2ASMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL13544042 | 0.77 | MMP1 (0.44) | MEN1KMT2ASMN1; SMN2L3MBTL1MMP1 | |
| SCHEMBL27813858 | 0.77 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL14943189 | 0.76 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2L3MBTL1MMP1 | |
| SCHEMBL4442846 | 0.76 | KMT2A (0.60) | MEN1KMT2ASMN1; SMN2L3MBTL1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459003-B | Pyrazole amide derivatives | 帝人制药株式会社 | 2019-06-21 | — | — | CN | disclosed |