Phosphine

Phosphine

SCHEMBL28301588

CCCCCCCCCCCCCCCCC=C=S.P

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.40
FAAH O00519 2/20 0.39
TRPV1 Q8NER1 1/20 0.39
NAAA Q02083 1/20 0.39
DNM1 Q05193 4/20 0.38
EP300 Q09472 1/20 0.35
GMNN O75496 1/20 0.34
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX15 P16050 1/20 0.34
APEX1 P27695 1/20 0.34
CYP2C19 P33261 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9582735 0.97
SCHEMBL11570828 0.97 TSHR (0.46) TSHRTHRBFAAHTRPV1NAAA
SCHEMBL2204770 0.97 TSHR (0.46) TSHRTHRBFAAHTRPV1NAAA
SCHEMBL11388796 0.97 TSHR (0.46) TSHRTHRBFAAHTRPV1NAAA
SCHEMBL4602943 0.95
SCHEMBL673584 0.87
SCHEMBL5521453 0.76 FAAH (0.46) TSHRFAAHTRPV1GMNNUSP2
SCHEMBL6880256 0.76 FAAH (0.46) TSHRFAAHTRPV1GMNNUSP2
SCHEMBL14809663 0.76 FAAH (0.46) TSHRFAAHTRPV1GMNNUSP2
SCHEMBL20482020 0.76 FAAH (0.46) TSHRFAAHTRPV1GMNNUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790013-A The solution of two chalcogenide nanoparticle of stratiform transition metal is combined to 纳米2D材料有限公司 2019-05-21 CN disclosed