SCHEMBL2830166

SCHEMBL2830166

Oc1ccc2cc(O)cc-2cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 4/20 0.77
ABCB1 P08183 4/20 0.77
BCR P11274 4/20 0.77
ESR1 P03372 7/20 0.67
ESR2 Q92731 6/20 0.67
HSD17B1 P14061 3/20 0.65
HSD17B2 P37059 3/20 0.65
MEN1 O00255 3/20 0.63
KMT2A Q03164 3/20 0.63
ALOX5 P09917 1/20 0.60
CYP3A4 P08684 3/20 0.57
NPC1 O15118 2/20 0.57
MAPT P10636 2/20 0.57
NFKB1 P19838 2/20 0.57
RAB9A P51151 2/20 0.57
KDM4E B2RXH2 1/20 0.57
CA12 O43570 1/20 0.57
GMNN O75496 1/20 0.57
ALDH1A1 P00352 1/20 0.57
CA1 P00915 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379088 0.87 ABL1 (1.00) ABL1ABCB1BCRESR1ESR2
SCHEMBL17081084 0.87 ABL1 (0.88) ABL1ABCB1BCRESR1ESR2
Phloroglucinol SCHEMBL11130971 0.81 ALDH1A1 (0.73) ABL1ABCB1BCRESR1ESR2
Hydroquinone SCHEMBL5712110 0.81 ESR1 (1.00) ABL1ABCB1BCRESR1ESR2
SCHEMBL30826784 0.81 ESR1 (1.00) ABL1ABCB1BCRESR1ESR2
SCHEMBL9090705 0.81 ESR1 (1.00) ABL1ABCB1BCRESR1ESR2
SCHEMBL15632 0.81 ESR1 (1.00) ABL1ABCB1BCRESR1ESR2
SCHEMBL368272 0.81 ESR1 (1.00) ABL1ABCB1BCRESR1ESR2
SCHEMBL6292004 0.81 ESR1 (1.00) ABL1ABCB1BCRESR1ESR2
SCHEMBL4432983 0.81 ESR1 (1.00) ABL1ABCB1BCRESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2069438-A None JP disclosed
JP-2069441-A None JP disclosed
JP-2069437-A None JP disclosed
CN-109929564-A Liquid-crystalline medium and liquid-crystal display 默克专利股份有限公司 2019-06-25 CN disclosed
CN-101080480-B Liquid crystal system and liquid crystal display 默克专利股份有限公司 2017-08-08 CN disclosed
EP-1896552-B1 LIQUID CRYSTAL MOLECULES COMPRISING HYDROAZULENE STRUCTURES TETRAGON CHEMIE AG (LI) 2010-05-19 EP disclosed
JP-H0269441-A AZULENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME DERIVATIVE MITSUBISHI KASEI CORP 1990-03-08 JP disclosed
JP-H0269437-A AZULENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME DERIVATIVE MITSUBISHI KASEI CORP 1990-03-08 JP disclosed
JP-H0269438-A AZULENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME DERIVATIVE MITSUBISHI KASEI CORP 1990-03-08 JP disclosed