Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorene SCHEMBL27935917 | 0.87 | PTGS2 (0.52) | CYP11B1CYP11B2CYP19A1CYP17A1ALDH1A1 | |
| SCHEMBL31498305 | 0.86 | CYP11B1 (0.52) | CYP11B1CYP11B2CYP19A1CYP17A1ALDH1A1 | |
| SCHEMBL20541087 | 0.85 | CYP2A6 (0.70) | CYP11B1CYP11B2CYP19A1CYP17A1ALDH1A1 | |
| SCHEMBL30026143 | 0.85 | CYP2A6 (0.70) | CYP11B1CYP11B2CYP19A1CYP17A1ALDH1A1 | |
| SCHEMBL12853987 | 0.83 | CYP2A6 (0.67) | CYP11B1CYP11B2CYP19A1CYP17A1ALDH1A1 | |
| SCHEMBL21110859 | 0.83 | CYP2A6 (0.67) | CYP11B1CYP11B2CYP19A1CYP17A1ALDH1A1 | |
| SCHEMBL31017586 | 0.81 | CYP2A6 (0.64) | CYP11B1CYP11B2CYP19A1ALDH1A1CYP2A6 | |
| SCHEMBL4621666 | 0.81 | CYP2A6 (0.64) | CYP11B1CYP11B2CYP19A1ALDH1A1CYP2A6 | |
| SCHEMBL29543420 | 0.79 | CYP2A6 (0.61) | CYP11B1CYP11B2CYP19A1CYP17A1ALDH1A1 | |
| SCHEMBL472043 | 0.79 | CYP2A6 (0.61) | CYP11B1CYP11B2CYP19A1CYP17A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107033189-B | Platinum (II) complex and preparation method and application thereof | 南京工业大学 | 2019-06-25 | — | — | CN | disclosed |