Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28111423 | 0.98 | TSHR (0.45) | TSHRNAPRTTDP1CYP2E1CYP3A4 | |
| Pyridine SCHEMBL28198537 | 0.93 | TSHR (0.41) | TSHRNAPRTTDP1CYP2E1CYP3A4 | |
| Pyridine SCHEMBL28271608 | 0.89 | TSHR (0.38) | TSHRNAPRTTDP1CYP2E1CYP3A4 | |
| Pyridine SCHEMBL28092021 | 0.87 | TSHR (0.36) | TSHRNAPRTTDP1CYP2E1CYP3A4 | |
| Bromide SCHEMBL30405465 | 0.82 | — | — | |
| Pyridine SCHEMBL28826022 | 0.79 | TSHR (0.41) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL28151461 | 0.79 | TBXAS1 (0.44) | TSHRNAPRTTDP1 | |
| SCHEMBL28568719 | 0.76 | — | — | |
| Pyridine SCHEMBL27871778 | 0.76 | TDP1 (0.64) | TSHRNAPRTTDP1 | |
| Ammonia Solution, Strong SCHEMBL27859174 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109971410-A | Adhesive composition, its solution, adhesive phase and surface protection film | 三星SDI株式会社 | 2019-07-05 | — | — | CN | disclosed |