Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexaethylene Glycol SCHEMBL16673171 | 0.91 | MEN1 (0.61) | MEN1KMT2ATSHRTDP1MAPK1 | |
| Propylene Glycol SCHEMBL8851429 | 0.91 | MEN1 (0.61) | MEN1KMT2ATSHRTDP1MAPK1 | |
| Triethylene Glycol SCHEMBL1073837 | 0.91 | MEN1 (0.61) | MEN1KMT2ATSHRTDP1MAPK1 | |
| Propylene Glycol SCHEMBL3359839 | 0.91 | MEN1 (0.61) | MEN1KMT2ATSHRTDP1MAPK1 | |
| Triethylene Glycol SCHEMBL6869496 | 0.91 | MEN1 (0.61) | MEN1KMT2ATSHRTDP1MAPK1 | |
| Triethylene Glycol SCHEMBL8013235 | 0.91 | MEN1 (0.61) | MEN1KMT2ATSHRTDP1MAPK1 | |
| Tetraethylene Glycol SCHEMBL8850597 | 0.91 | MEN1 (0.61) | MEN1KMT2ATSHRTDP1MAPK1 | |
| Propylene Glycol SCHEMBL8851056 | 0.91 | MEN1 (0.61) | MEN1KMT2ATSHRTDP1MAPK1 | |
| Triethylene Glycol SCHEMBL22077278 | 0.91 | MEN1 (0.61) | MEN1KMT2ATSHRTDP1MAPK1 | |
| SCHEMBL4854810 | 0.89 | MEN1 (0.48) | MEN1KMT2ATSHRTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473259-B | Metallic copper dispersion liquid, Its Preparation Method And Use | 石原产业株式会社 | 2019-06-21 | — | — | CN | disclosed |
| CN-108445713-A | Photosensitive polymer combination defines layer and display device using its black picture element | 三星SDI株式会社 | 2018-08-24 | — | — | CN | disclosed |