Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5590404 | 0.67 | HTT (0.47) | TDP1HPGDNPC1MAPK1HTT | |
| SCHEMBL18554673 | 0.67 | ALOX5 (0.45) | TDP1ESR1HPGDNPC1MAPK1 | |
| SCHEMBL5588839 | 0.66 | HPGD (0.41) | ESR1HPGDNPC1MAPK1HTT | |
| SCHEMBL22248704 | 0.66 | TYR (0.43) | TDP1ESR1HPGDNPC1MAPK1 | |
| SCHEMBL11304485 | 0.66 | HPGD (0.42) | TDP1ESR1HPGDNPC1MAPK1 | |
| SCHEMBL21286970 | 0.66 | HTT (0.43) | ESR1HPGDNPC1MAPK1HTT | |
| SCHEMBL7926662 | 0.64 | TDP1 (0.54) | TDP1ESR1HTTEYA3TTR | |
| SCHEMBL6674151 | 0.64 | MAPT (0.34) | HPGDALDH1A1HSD17B10ALOX5 | |
| SCHEMBL5589559 | 0.63 | HPGD (0.41) | ESR1HPGDNPC1MAPK1HTT | |
| SCHEMBL8010899 | 0.63 | ALOX5 (0.43) | ESR1KDM4EALDH1A1HSD17B10ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988131-A | The preparation method of Amiodarone Hydrochloride | 浙江普利药业有限公司 | 2019-07-09 | — | — | CN | disclosed |