Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306761 | 0.82 | APP (0.39) | MAPTKMT2AALDH1A1MEN1PKM | |
| SCHEMBL28306750 | 0.75 | MAPT (0.44) | MAPTKMT2AALDH1A1MEN1PKM | |
| SCHEMBL806444 | 0.69 | RELA (0.60) | MAPTKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL21922852 | 0.69 | RELA (0.60) | MAPTKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL275803 | 0.69 | RELA (0.60) | MAPTKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL101911 | 0.69 | RELA (0.60) | MAPTKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL275802 | 0.69 | RELA (0.60) | MAPTKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL14018370 | 0.69 | RELA (0.60) | MAPTKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL14526617 | 0.69 | RELA (0.60) | MAPTKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL13927945 | 0.69 | RELA (0.60) | MAPTKMT2AALDH1A1MEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028456-B | Barbituric acid derivative and preparation method and application thereof | 齐鲁工业大学 | 2021-02-23 | — | — | CN | disclosed |
| CN-110028456-A | A kind of barbituric acid derivatives and preparation method and application | 齐鲁工业大学 | 2019-07-19 | — | — | CN | disclosed |