Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28305806 | 0.91 | SRC (0.56) | SRCCYP2D6LMNAMAPK1CYP1A2 | |
| SCHEMBL10707628 | 0.83 | SRC (0.70) | SRCCYP2D6LMNAMAPK1CYP1A2 | |
| SCHEMBL148725 | 0.79 | SRC (1.00) | SRCCYP2D6LMNAMAPK1CYP1A2 | |
| SCHEMBL70165 | 0.79 | SRC (1.00) | SRCCYP2D6LMNAMAPK1CYP1A2 | |
| SCHEMBL2914808 | 0.79 | KMT2A (0.64) | SRCCYP2D6LMNAMAPK1KMT2A | |
| SCHEMBL27389855 | 0.78 | L3MBTL1 (0.56) | SRCCYP2D6LMNACYP1A2PKM | |
| SCHEMBL1925703 | 0.78 | SRC (0.42) | SRCCYP2D6LMNACYP1A2PKM | |
| SCHEMBL1581315 | 0.78 | SRC (0.76) | SRCCYP2D6LMNAMAPK1CYP1A2 | |
| SCHEMBL9686394 | 0.78 | SRC (0.61) | SRCCYP2D6LMNAMAPK1CYP1A2 | |
| SCHEMBL6439691 | 0.78 | SRC (0.61) | SRCCYP2D6LMNAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988113-A | A kind of synthetic method of [60] fullerene tetrahydroquinoline derivative | 河南师范大学 | 2019-07-09 | — | — | CN | disclosed |