Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307015 | 0.89 | GAA (0.68) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL28874980 | 0.88 | GAA (0.67) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL28308026 | 0.84 | GAA (0.65) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL28162015 | 0.83 | GAA (1.00) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL28307038 | 0.80 | GAA (0.57) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL3002780 | 0.71 | GAA (0.78) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL6706771 | 0.71 | GAA (0.73) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL8084149 | 0.71 | GAA (0.67) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL28307990 | 0.69 | GAA (0.57) | GAAKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL3002479 | 0.67 | GAA (0.71) | GAAKMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866610-B | A kind of 2- amino chromene derivative N- alkylation that Lewis/Bronsted acid promotes lower alcohol to participate in | 齐齐哈尔大学 | 2019-06-25 | — | — | CN | disclosed |