Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MET | P08581 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3002780 | 0.88 | GAA (0.78) | GAAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL6706771 | 0.84 | GAA (0.73) | GAAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL3002479 | 0.83 | GAA (0.71) | GAAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL28307012 | 0.83 | GAA (0.71) | GAAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL18719845 | 0.81 | GAA (0.69) | GAAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL3004197 | 0.81 | GAA (0.69) | GAAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL28307015 | 0.81 | GAA (0.68) | GAAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL3007061 | 0.81 | ALDH1A1 (0.68) | GAAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL28874980 | 0.80 | GAA (0.67) | GAAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL8084149 | 0.80 | GAA (0.67) | GAAALDH1A1TSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107216305-B | Benzopyran compounds and application thereof | 中国人民解放军第四军医大学 | 2020-05-08 | — | — | CN | disclosed |
| CN-107216305-A | Benzopyran class compound and its application | 中国人民解放军第四军医大学 | 2017-09-29 | — | — | CN | disclosed |