Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.58 |
| ▸ | ACHE | P22303 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1754049 | 0.77 | NOTUM (0.53) | BCHEACHEPOLBL3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL27756629 | 0.76 | NOTUM (0.51) | BCHEACHEPOLBL3MBTL1TDP1 | |
| SCHEMBL5026715 | 0.73 | NOTUM (0.51) | BCHEACHEL3MBTL1TSHRMAPK1 | |
| SCHEMBL7409297 | 0.72 | POLB (0.66) | POLBL3MBTL1NPC1TP53MAPT | |
| SCHEMBL11193164 | 0.70 | NOTUM (0.49) | BCHEACHEPOLBL3MBTL1TDP1 | |
| SCHEMBL27511390 | 0.70 | TAAR1 (0.49) | BCHEACHEPOLBL3MBTL1ADRB3 | |
| SCHEMBL28119066 | 0.70 | BCHE (0.56) | BCHEPOLBTP53MAPTMAPK1 | |
| SCHEMBL30308650 | 0.70 | NPC1 (0.48) | BCHEACHEPOLBL3MBTL1NPC1 | |
| SCHEMBL11407839 | 0.69 | BCHE (0.54) | BCHEPOLBL3MBTL1TP53MAPT | |
| SCHEMBL4404820 | 0.69 | NPC1 (0.58) | POLBL3MBTL1NPC1TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023304-A | Calpain regulator and its therapeutical uses | 布莱德治疗公司 | 2019-07-16 | — | — | CN | disclosed |