Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219953 | 0.86 | GRM2 (0.53) | GRM2GRM3SMN1; SMN2HIF1AKEAP1 | |
| SCHEMBL11088109 | 0.86 | GRM2 (0.53) | GRM2GRM3SMN1; SMN2HIF1AKEAP1 | |
| SCHEMBL7441576 | 0.86 | GRM2 (0.53) | GRM2GRM3SMN1; SMN2HIF1AKEAP1 | |
| SCHEMBL20049736 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2HIF1ATAAR1MAPTPLA2G10 | |
| SCHEMBL9190217 | 0.79 | GRM2 (0.46) | GRM2GRM3SMN1; SMN2HIF1AKEAP1 | |
| SCHEMBL27957913 | 0.79 | AR (0.47) | GRM2GRM3SMN1; SMN2KEAP1LMNA | |
| SCHEMBL6344201 | 0.79 | SRC (0.45) | GRM2GRM3SMN1; SMN2HIF1ALMNA | |
| SCHEMBL6341497 | 0.79 | SRC (0.45) | GRM2GRM3SMN1; SMN2HIF1ALMNA | |
| SCHEMBL6803588 | 0.78 | HDAC3 (0.50) | GRM2GRM3SMN1; SMN2HIF1AKEAP1 | |
| SCHEMBL28681602 | 0.77 | SMN1; SMN2 (0.48) | GRM2GRM3SMN1; SMN2HIF1AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023304-A | Calpain regulator and its therapeutical uses | 布莱德治疗公司 | 2019-07-16 | — | — | CN | disclosed |