Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28208793 | 0.89 | LMNA (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22984079 | 0.88 | KMT2A (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27478411 | 0.87 | LTB4R (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL30080837 | 0.86 | CYP1A2 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL173883 | 0.86 | CYP1A2 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5320849 | 0.85 | MAPT (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9190217 | 0.85 | GRM2 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27957913 | 0.85 | AR (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28246708 | 0.84 | LTB4R (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8287226 | 0.84 | ALDH1A1 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240240025-A1 | Blue-Excitable Water-Solvated Polymeric Dyes | BECTON, DICKINSON AND COMPANY | 2024-07-18 | — | — | US | disclosed |
| CN-106232585-B | Triaizine compounds and its medicinal usage | 日本烟草产业株式会社 | 2019-04-02 | — | — | CN | disclosed |
| CN-109280074-A | Dan Nuoruiwei sodium crystal and preparation method thereof | 歌礼药业（浙江）有限公司 | 2019-01-29 | — | — | CN | disclosed |
| CN-105367482-B | N acyl sulfonamides apoptosis accelerator | 阿斯利康(瑞典)有限公司 | 2017-12-12 | — | — | CN | disclosed |
| CN-105367482-A | N-acylsulfamide apoptosis accelerator | ASTRAZENECA AB | 2016-03-02 | — | — | CN | disclosed |
| CN-103153954-B | N-acylsulfonamide apoptosis promoters | ASTRAZENECA AB (SE) | 2015-11-25 | — | — | CN | disclosed |
| EP-2718284-A1 | TRIAZOLONE COMPOUNDS AS mPGES-1 INHIBITORS | Glenmark Pharmaceuticals S.A. (CH) | 2014-04-16 | — | — | EP | disclosed |
| WO-2013186692-A1 | TRIAZOLONE COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-12-19 | — | — | WO | disclosed |
| WO-2004113351-A2 | BIFUNCTIONAL AMINO-BORON LEWIS ACID - LEWIS BASE CATALYST | UNIVERSITY OF DURHAM (GB) | 2004-12-29 | — | — | WO | disclosed |
| WO-1999025682-A1 | ELEVATION OF HDL CHOLESTEROL BY 4-[(AMINOTHIOXOMETHYL) -HYDRAZONO] -N-(SUBSTITUTED) -4-ARYLBUTANAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-05-27 | — | — | WO | disclosed |