Naphthalene

Naphthalene

SCHEMBL28307374

COC(=O)O.c1ccc2ccccc2c1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
KMT2A Q03164 2/20 0.48
KCNN4 O15554 1/20 0.48
KDM4E B2RXH2 2/20 0.47
HPGD P15428 2/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP2A6 P11509 2/20 0.44
ALOX12 P18054 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
SRC P12931 1/20 0.43
LMNA P02545 1/20 0.43
HSP90AA1 P07900 1/20 0.42
PAX8 Q06710 1/20 0.42
HSD17B10 Q99714 2/20 0.42
CYP1A2 P05177 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
MAPT P10636 3/20 0.42
RAB9A P51151 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthracene SCHEMBL6509397 0.90 KDM4E (0.53) TSHRKMT2AKCNN4KDM4EHPGD
Naphthalene SCHEMBL27476939 0.84 TSHR (0.50) TSHRKMT2AKCNN4KDM4EHPGD
Naphthalene SCHEMBL1961577 0.83 ALDH1A1 (0.56) TSHRKMT2AKCNN4KDM4EHPGD
Biphenyl SCHEMBL3255863 0.83 TSHR (0.54) TSHRKMT2AKCNN4ALDH1A1SLC6A2
Benzene SCHEMBL28156248 0.82 TSHR (0.48) TSHRKMT2AKCNN4KDM4EHPGD
Phenol SCHEMBL25374179 0.81 CA12 (0.58) TSHRKMT2AKCNN4HPGDSRC
Catechol SCHEMBL27621256 0.81 TSHR (0.58) TSHRKMT2AKCNN4KDM4EHPGD
Phenol SCHEMBL18603299 0.81 CA12 (0.58) TSHRKMT2AKCNN4HPGDSRC
Naphthalene SCHEMBL27334337 0.81 TSHR (0.46) TSHRKMT2AKCNN4KDM4EHPGD
Naphthalene SCHEMBL1629195 0.80 CYP2A6 (0.47) TSHRKMT2AKDM4EHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109937197-A Electrochemical process for preparing aryl alkyl carbonates and diaryl carbonates 科思创德国股份有限公司 2019-06-25 CN disclosed