Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27533330 | 0.80 | MAPT (0.31) | MAPT | |
| SCHEMBL15730093 | 0.73 | GAA (0.64) | GAATSHRRECQLMAPTALDH1A1 | |
| SCHEMBL6185245 | 0.73 | GAA (0.64) | GAATSHRRECQLMAPTALDH1A1 | |
| SCHEMBL16254691 | 0.73 | GAA (0.64) | GAATSHRRECQLMAPTALDH1A1 | |
| SCHEMBL15730586 | 0.73 | GAA (0.64) | GAATSHRRECQLMAPTALDH1A1 | |
| SCHEMBL26537946 | 0.72 | GPR119 (0.41) | RECQLSMN1; SMN2 | |
| SCHEMBL5762755 | 0.72 | GPR119 (0.41) | RECQLSMN1; SMN2 | |
| SCHEMBL16254880 | 0.72 | TSHR (0.66) | GAATSHRRECQLMAPTALDH1A1 | |
| SCHEMBL9093412 | 0.72 | TSHR (0.66) | GAATSHRRECQLMAPTALDH1A1 | |
| SCHEMBL9667551 | 0.70 | GAA (0.95) | GAATSHRRECQLMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715416-B | The pyrrolopyridine regulator and its application method that the methyl and trifluoromethyl of RORC2 replaces | 辉瑞大药厂 | 2019-07-23 | — | — | CN | disclosed |