Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22342099 | 0.91 | PDE4B (0.39) | IDO1KMT2AMEN1HTTNPSR1 | |
| SCHEMBL17786110 | 0.82 | PARP1 (0.44) | KMT2AMEN1HTTNPSR1MAPT | |
| SCHEMBL29253795 | 0.79 | HTR1D (0.46) | CYP3A4CYP2D6MAPK1LMNAHTR6 | |
| SCHEMBL26606681 | 0.78 | HTT (0.39) | IDO1KMT2AMEN1HTTNPSR1 | |
| SCHEMBL4181291 | 0.76 | CD44 (0.41) | IDO1CYP3A4CYP2D6TSHRMAPK1 | |
| SCHEMBL550734 | 0.74 | SLC18A3 (0.53) | CYP2D6CYP2C19HTR6 | |
| SCHEMBL17786108 | 0.73 | PARP1 (0.44) | KMT2AMEN1HTTNPSR1MAPT | |
| SCHEMBL28308329 | 0.73 | KDM4E (0.47) | CYP3A4CYP2D6MAPK1LMNAHTR6 | |
| SCHEMBL28825795 | 0.73 | CD44 (0.34) | — | |
| SCHEMBL8279878 | 0.73 | DRD2 (0.61) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110049983-A | Medical compounds | 细胞中心有限公司 | 2019-07-23 | — | — | CN | disclosed |