Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27618733 | 0.89 | — | — | |
| Oxalic Acid SCHEMBL283116 | 0.84 | ALOX15 (1.00) | ALOX15KDM4ETDP1MMP2ALDH1A1 | |
| Oxalic Acid SCHEMBL10707552 | 0.84 | ALOX15 (1.00) | ALOX15KDM4ETDP1MMP2ALDH1A1 | |
| SCHEMBL31975 | 0.82 | — | — | |
| Trifluoroacetic Acid SCHEMBL27997235 | 0.80 | ALOX15 (0.50) | ALOX15CTSDKDM4CHDAC3HDAC1 | |
| Trifluoroacetic Acid SCHEMBL7455642 | 0.80 | ALOX15 (0.50) | ALOX15CTSDKDM4CHDAC3HDAC1 | |
| Acrylic Acid SCHEMBL27551325 | 0.80 | ALOX15 (0.50) | ALOX15CTSDKDM4ETDP1MMP1 | |
| Oxalic Acid SCHEMBL55207 | 0.79 | ALOX15 (0.59) | ALOX15CTSDKDM4ETDP1MMP1 | |
| Water SCHEMBL11719073 | 0.78 | — | — | |
| Butane SCHEMBL888569 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108746656-B | Pre-alloyed powder for diamond products and preparation method thereof | 威海职业学院 | 2021-11-26 | — | — | CN | claimed |
| CN-108746656-A | Prealloy powder and preparation method thereof for diamond composition | 威海职业学院 | 2018-11-06 | — | — | CN | claimed |
| CN-108746656-A | Prealloy powder and preparation method thereof for diamond composition | 威海职业学院 | 2018-11-06 | — | — | CN | disclosed |
| EP-1646095-B2 | Stabilised silver nanoparticles and their use | XEROX CORP (US) | 2018-10-17 | — | — | EP | disclosed |
| EP-2526098-B1 | NITROGEN-CONTAINING HETEROARYL DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2018-07-11 | — | — | EP | disclosed |
| EP-2697203-B1 | MINERALOCORTICOID RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2017-05-24 | — | — | EP | disclosed |
| US-9487506-B2 | Mineralocorticoid receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2016-11-08 | — | — | US | disclosed |
| EP-2440554-B1 | PYRAZOLE OXADIAZOLE DERIVATIVES AS S1P1 AGONISTS | MERCK SERONO SA (CH) | 2016-10-05 | — | — | EP | disclosed |
| EP-1696912-B1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2016-05-11 | — | — | EP | disclosed |
| EP-1646095-B1 | Stabilised silver nanoparticles and their use | XEROX CORP (US) | 2016-03-09 | — | — | EP | disclosed |
| EP-2428507-B1 | Cannabinoid receptor ligands | ABBVIE BAHAMAS LTD (BS) | 2015-10-21 | — | — | EP | disclosed |
| WO-1993007149-A1 | PYRAZOLOPYRIMIDINONE ANTIANGINAL AGENTS | PFIZER LIMITED (GB) | 1993-04-15 | — | — | WO | disclosed |
| US-5120347-A | Pre and postemergence | ROHM AND HAAS COMPANY (US) | 1992-06-09 | — | — | US | disclosed |
| US-4920128-A | TREATMENT OF HERPES VIRUS | STERLING DRUG INC. (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0001144-B1 | N-SUBSTITUTED 2-HYDRAZONO-PROPIONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1981-06-17 | — | — | EP | disclosed |
| US-4206231-A | Hypoglycaemically active 2-alkyl- or -alkenyl-hydrazono propionic acid derivatives | BOEHRINGER MANNHEIM GMBH (DE) | 1980-06-03 | — | — | US | disclosed |
| EP-0001144-A1 | N-substituted 2-hydrazono-propionic acid derivatives, process for their preparation and pharmaceutical compositions containing them | Roche Diagnostics GmbH (DE) | 1979-03-21 | — | — | EP | disclosed |
| US-4075222-A | VETERINARY MEDICINE, BACTERICIDES, FUNGICIDES, ANTIPROTOZOAN | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-3980794-A | Method for promoting growth of poultry with 3-(5-nitro-2-imidazolyl)pyrazoles | ELI LILLY AND COMPANY (US) | 1976-09-14 | — | — | US | disclosed |
| US-3947467-A | ANTIBACTERIAL, ANTIPROTOZOAL, ANTIFUNGAL | ELI LILLY AND COMPANY (US) | 1976-03-30 | — | — | US | disclosed |