SCHEMBL28307665

SCHEMBL28307665

NCc1c(F)[c]ccc1F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27694496 0.78 TAAR1 (0.38) TAAR1
SCHEMBL27694458 0.78 TAAR1 (0.38) TAAR1
SCHEMBL28104343 0.78
SCHEMBL576902 0.77
SCHEMBL247314 0.74 KDM4E (0.31)
Hydrochloric Acid SCHEMBL5472476 0.70 TAAR1 (0.52) TAAR1LOXL2
SCHEMBL27916286 0.70 TAAR1 (0.42) TAAR1
SCHEMBL29199639 0.69
SCHEMBL20487629 0.68 LOXL2 (0.31) LOXL2
SCHEMBL28073430 0.68 LOXL2 (0.36) LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110062761-A Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and their use as GLUN2B receptor modulators 詹森药业有限公司 2019-07-26 CN disclosed