Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 19/20 | 0.51 |
| ▸ | HSD11B2 | P80365 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2824322 | 0.84 | HSD11B1 (0.65) | HSD11B1HSD11B2 | |
| SCHEMBL2827911 | 0.82 | HSD11B1 (0.59) | HSD11B1HSD11B2 | |
| SCHEMBL2827913 | 0.82 | HSD11B1 (0.59) | HSD11B1HSD11B2 | |
| SCHEMBL2827915 | 0.81 | HSD11B1 (0.51) | HSD11B1HSD11B2GAA | |
| SCHEMBL231705 | 0.81 | HSD11B1 (0.77) | HSD11B1HSD11B2 | |
| SCHEMBL2833830 | 0.77 | HSD11B1 (0.51) | HSD11B1HSD11B2 | |
| SCHEMBL2824723 | 0.77 | HSD11B1 (0.50) | HSD11B1HSD11B2 | |
| SCHEMBL2836250 | 0.77 | HSD11B1 (0.54) | HSD11B1HSD11B2 | |
| SCHEMBL2824343 | 0.75 | HSD11B1 (0.63) | HSD11B1HSD11B2 | |
| SCHEMBL2827493 | 0.74 | HSD11B1 (0.51) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243479-A2 | Novel amide and amidine derivates and uses thereof | Abbott Laboratories (US) | 2010-10-27 | — | — | EP | disclosed |