Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28279923 | 0.84 | TNKS2 (0.58) | PARP1TNKS2 | |
| SCHEMBL28308034 | 0.84 | PARP1 (0.57) | PARP1GPR84PARP2TNKS2 | |
| SCHEMBL28307043 | 0.84 | PARP1 (0.57) | PARP1GPR84POLBPARP2TNKS2 | |
| SCHEMBL27764706 | 0.84 | PARP1 (0.57) | PARP1GPR84 | |
| SCHEMBL1586541 | 0.77 | PARP1 (0.91) | PARP1PARP2TNKS2 | |
| SCHEMBL30176861 | 0.76 | PARP1 (0.89) | PARP1PARP2TNKS2 | |
| SCHEMBL14621928 | 0.76 | PARP1 (0.89) | PARP1PARP2TNKS2 | |
| SCHEMBL22857122 | 0.76 | PARP1 (0.89) | PARP1PARP2TNKS2 | |
| SCHEMBL30176973 | 0.76 | PARP1 (0.89) | PARP1PARP2TNKS2 | |
| SCHEMBL28598382 | 0.76 | PARP1 (0.89) | PARP1PARP2TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041306-A | 4- hydroxyl -2- quinolone-nitrogen-(4- quinazolinone) -3- carboxamides derivatives | 中国医学科学院药物研究所 | 2019-07-23 | — | — | CN | disclosed |