Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.58 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.49 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 4/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28308017 | 0.84 | PARP1 (0.57) | TNKS2PARP1 | |
| SCHEMBL17298073 | 0.81 | PARP1 (0.65) | TNKS2ACVR1DDAH1PARP1ADORA3 | |
| SCHEMBL13892327 | 0.78 | TNKS2 (0.57) | TNKS2ACVR1DDAH1PARP1ADORA3 | |
| SCHEMBL21185367 | 0.77 | TNKS2 (0.52) | TNKS2ACVR1DDAH1PARP1ADORA3 | |
| SCHEMBL14080068 | 0.76 | TYMS (0.70) | TYMS | |
| SCHEMBL61188 | 0.75 | TNKS2 (0.50) | TNKS2ACVR1DDAH1ADORA3L3MBTL1 | |
| SCHEMBL3826724 | 0.73 | TNKS2 (1.00) | TNKS2DDAH1PARP1ALDH1A1KDM4E | |
| SCHEMBL30176850 | 0.73 | TNKS2 (1.00) | TNKS2DDAH1PARP1ALDH1A1KDM4E | |
| SCHEMBL28113233 | 0.72 | TNKS (0.61) | TNKS2PARP1ALDH1A1NPC1GAA | |
| SCHEMBL17298090 | 0.69 | TNKS2 (0.62) | TNKS2PARP1ADORA3TYMSL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384731-B | Method for preparing quinazolinone from enol | 南京理工大学 | 2021-10-08 | — | — | CN | disclosed |
| CN-109384731-A | A method of quinazolinone is prepared by enol | 南京理工大学 | 2019-02-26 | — | — | CN | disclosed |