Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17679790 | 0.88 | TSHR (0.41) | TSHRTTRALBKMT2AALDH1A1 | |
| SCHEMBL20097982 | 0.86 | TSHR (0.39) | TSHRTTRALBKMT2AMEN1 | |
| SCHEMBL119203 | 0.84 | TSHR (0.50) | TSHRKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL2222375 | 0.83 | TSHR (0.41) | TSHRTTRALBKMT2AMEN1 | |
| SCHEMBL10098510 | 0.79 | TSHR (0.46) | TSHRKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL4203403 | 0.79 | TSHR (0.46) | TSHRKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL5945887 | 0.76 | TSHR (0.48) | TSHRKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL17679946 | 0.76 | TTR (0.39) | TSHRTTRALBKMT2AMEN1 | |
| SCHEMBL1685558 | 0.76 | TTR (0.37) | TSHRTTRALDH1A1TDP1 | |
| SCHEMBL8954330 | 0.73 | TSHR (0.50) | TSHRKMT2AMEN1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110093382-B | Chemical-biological preparation method of illicit-lin chiral intermediate | 尚科生物医药（上海）有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-110092735-B | Preparation method of L-alanine derivative | 尚科生物医药（上海）有限公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-110093382-A | A kind of chemical-biological preparation method of Yi Luduo quinoline chiral intermediate | 尚科生物医药（上海）有限公司 | 2019-08-06 | — | — | CN | disclosed |
| CN-110092735-A | A kind of preparation method of l-Alanine derivative | 尚科生物医药（上海）有限公司 | 2019-08-06 | — | — | CN | disclosed |