Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28308989 | 0.81 | KDM4E (0.45) | KDM4EMAPTCYP19A1TBXAS1ALDH1A1 | |
| SCHEMBL3136413 | 0.80 | KDM4E (0.56) | KDM4EMAPTCYP19A1TBXAS1ALDH1A1 | |
| SCHEMBL12749711 | 0.77 | KDM4E (0.48) | KDM4EMAPTCYP19A1TBXAS1ALDH1A1 | |
| SCHEMBL5495469 | 0.75 | CYP19A1 (0.54) | KDM4EMAPTCYP19A1TBXAS1ALDH1A1 | |
| SCHEMBL3817705 | 0.74 | MAPT (0.54) | KDM4EMAPTCYP19A1TBXAS1ALDH1A1 | |
| SCHEMBL23844520 | 0.74 | KDM4E (0.41) | KDM4EMAPTCYP19A1TBXAS1ALDH1A1 | |
| SCHEMBL5583861 | 0.74 | KDM4E (0.42) | KDM4EMAPTALDH1A1LMNAHTT | |
| SCHEMBL14456318 | 0.74 | KDM4E (0.38) | KDM4EMAPTMEN1KMT2ASCN9A | |
| SCHEMBL14656677 | 0.74 | CYP1A2 (0.42) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9183907 | 0.73 | LOXL2 (0.61) | KDM4EMAPTALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814040-B | The condensed 1,4- dihydro two of inhibitor as thermal excited transcryption factor 1 dislikes ene derivative | 癌症研究科技有限公司 | 2019-07-30 | — | — | CN | disclosed |