Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10718782 | 0.82 | KDM5B (0.33) | ALDH1A1 | |
| SCHEMBL946316 | 0.82 | ALDH1A1 (0.32) | CDC7ALDH1A1ATM | |
| SCHEMBL15634282 | 0.78 | KDM4E (0.42) | GAAALDH1A1 | |
| SCHEMBL24117441 | 0.75 | GAA (0.35) | GAAALDH1A1 | |
| SCHEMBL10551288 | 0.74 | KDM4E (0.48) | GAAALDH1A1ATM | |
| SCHEMBL16660360 | 0.74 | — | — | |
| SCHEMBL17881859 | 0.73 | KDM5A (0.33) | — | |
| SCHEMBL918559 | 0.71 | — | — | |
| SCHEMBL164592 | 0.71 | — | — | |
| SCHEMBL9799881 | 0.71 | ALDH1A1 (0.34) | PARP1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110022875-A | Therapeutic inhibiting compound | 莱福斯希医药公司 | 2019-07-16 | — | — | CN | disclosed |