Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 3/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28324513 | 0.78 | NSD2 (0.33) | NSD2PTPN2PTPN1GPR3MEN1 | |
| SCHEMBL28253519 | 0.78 | NSD2 (0.33) | NSD2PTPN2PTPN1GPR3MEN1 | |
| SCHEMBL21400041 | 0.72 | LMNA (0.33) | GPR3MEN1KMT2A | |
| SCHEMBL12324811 | 0.67 | NSD2 (0.30) | NSD2PTPN2PTPN1 | |
| SCHEMBL17223955 | 0.64 | NSD2 (0.33) | NSD2HPGD | |
| SCHEMBL28325602 | 0.63 | KDM4E (0.37) | NSD2PTPN2PTPN1GPR3MEN1 | |
| SCHEMBL27678807 | 0.63 | PTPN2 (0.44) | NSD2PTPN2PTPN1GPR3MEN1 | |
| SCHEMBL28525064 | 0.62 | NOTUM (0.30) | — | |
| SCHEMBL21250753 | 0.62 | PDGFRB (0.46) | PTPN2PTPN1GPR3KDM4EPDGFRB | |
| SCHEMBL28015523 | 0.61 | MEN1 (0.40) | PTPN2PTPN1GPR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483492-A | Dipeptidyl peptidase i inhibitors | ASTRAZENECA AB | 2019-11-22 | — | — | CN | disclosed |
| CN-105980367-B | (2S) -N- [ (1S) -1-cyano-2-phenylethyl ] -1, 4-oxazepane-2-carboxamides as dipeptidyl peptidase I inhibitors | 阿斯利康(瑞典)有限公司 | 2019-08-23 | — | — | CN | disclosed |