Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.79 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.79 |
| ▸ | RELA | Q04206 | 4/20 | 0.79 |
| ▸ | NPC1 | O15118 | 8/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | CNR2 | P34972 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131467 | 0.89 | SMN1; SMN2 (1.00) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL31306421 | 0.87 | CNR2 (0.62) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL31295503 | 0.87 | RAB9A (0.60) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL7570608 | 0.86 | RAB9A (0.77) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL6037569 | 0.86 | RAB9A (0.77) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL6037573 | 0.86 | RAB9A (0.77) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL12258528 | 0.85 | SMN1; SMN2 (0.80) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL21446750 | 0.84 | RAB9A (0.73) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL14077911 | 0.83 | RAB9A (0.55) | RAB9ASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL8071379 | 0.83 | RAB9A (0.77) | RAB9ASMN1; SMN2NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156683-B | Synthesis method of quinoline oxide | 青岛农业大学 | 2020-06-26 | — | — | CN | disclosed |
| CN-110156683-A | The synthetic method of quinoline type oxide | 青岛农业大学 | 2019-08-23 | — | — | CN | disclosed |